Logistic Dysfunction (LOD) System - ANNEX III
					LOD Points
		Increasing Severity/ Decreasing Values		Organ Dysfunction Free		Increasing Severity/ Increasing Values
Organ System Measures	5	3	1	0	1	3	5
Neurologic
Glasgow Coma Score	3-5	6-8	9-13	14-15	...	...	...
Cardiovascular
Heart rate, beats/min	<30	...	...	30-139	³ 140	...	...
	or			and	or
Systolic Blood pressure, mm Hg	<40	40-69	70-89	90-239	240-269	³ 270	...
Renal
Serum urea, mmol/L (g/L)	...	...	...	<6 (<0.36)	6-9.9 (0.36-0.59)	10-19.9 (0.60-1.19)	³ 20 ( ³1.20)
or
Serum urea nitrogen, mmol/L (mg/dL)	...	...	...	<6 (<17)	6-9.9 (17-<28)	10-19.9 (28-<56)	³ 20 (³ 56)
				and	or	or
Creatinine, µmol/L (mg/dL)	...	...	...	<106 (<1.20)	106-140 (1.20-1.59)	³ 141 (³ 1.60)	...
				and		or
Urine Output, L/d	< 0.5	0.5-0.74	...	0.75-9.99	...	³ 10
Pulmonary
PaO2 (mm Hg)/FIO2 on MV or CPAP		< 150	³ 150	No ventilation	...	...	...
				no CPAP
(PaO2[kPa]/FIO2)		(<19.9)	( ³ 19.9)	no IPAP	...	...	...
Hematologic
White blood cell count, x 109/L	...	<1.0	1.0-2.4	2.5-49.9	³ 50.0	...	...
			or	and
Platelets, x109/L	...	...	<50	³ 50
Hepatic
Bilirubin, µmol/L (mg/dL)	...	...	...	<34.2(<2.0)	³ 34.2 (³ 2.0)	...	...
				and	or
Prothrombin time, s above	...	...	(<25 %)	£ 3 (³ 25 %)	>3	...	...
standard (% of standard)